The University of Cincinnati has used human tissue for their study on “average” BPA exposure. Their findings, though not surprising, supports other independent research that BPA does affect human health.
In a laboratory study, using fresh human fat tissues, the UC team found that BPA suppresses a key hormone, adiponectin, which is responsible for regulating insulin sensitivity in the body and puts people at a substantially higher risk for metabolic syndrome.
Metabolic syndrome is a combination of risk factors that include lower responsiveness to insulin and higher blood levels of sugar and lipids. According to the American Heart Association, about 25 percent of Americans have metabolic syndrome. Left untreated, the disorder can lead to life-threatening health problems such as coronary artery disease, stroke and type 2 diabetes.
Nira Ben-Jonathan, PhD, and her team are the first to report scientific evidence on the health effects of BPA at environmentally relevant doses equal to “average” human exposure. Previous studies have primarily focused on animal studies and high doses of BPA.
How was the study conducted?
…the UC team collected fresh fat tissue from Cincinnati patients undergoing several types of breast or abdominal surgery. These samples included three types of fat tissue: breast, subcutaneous and visceral (around the organs).
Tissue was immediately taken to the laboratory and incubated with different concentrations of BPA or estrogen for six hours to observe how the varied amounts of BPA affected adiponectin levels. The effects of BPA were then compared to those of estradiol, a natural form of human estrogen.
What were the results?
They found that exposing human tissues to BPA levels within the range of common human exposure resulted in suppression of a hormone that protects people from metabolic syndrome.
“These results are especially powerful because we didn’t use a single patient, a single tissue source or a single occurrence,” she adds. “We used different fat tissues from multiple patients and got the same negative response to BPA.”
Again, very interesting findings. This does support other independent research, yet the FDA still claims the safety of BPA. I am really not all that surprised, yet I am in shock. I cannot believe with all this mounting evidence, they can stand by that claim.
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